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+ 26 = 93 \text million miles - Crosslake

📅 March 1, 2026 👤 scraface

Mar 01, 2026

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📌 Cianflone’s career began in large-scale pharmaceutical R&D environments, where he played a key role in designing syntheses for commercial drug candidates. His deep experience spans both early-stage discovery and process development, with an emphasis on chemistry that is robust, scalable, and cost-effective.

📌 In 2012, Cianflone co-founded Celesta Biosciences, a biotechnology company developing connective tissue-targeted therapies. Celesta was acquired in 2014 by Actelion, now part of Janssen Pharmaceuticals, marking his first major exit as a founder. He then led the spinout and development of LampLabs, a precision chemistry laboratory specializing in the synthesis of complex molecules, holding appointments as Chief Technology Officer. At LampLabs, Cianflone championed innovation in synthesis technologies, contributing to novel analytical platforms and chemical manufacturing advances.

📌 Beyond Celesta and LampLabs, Cianflone has served in multiple entrepreneurial roles. He co-founded Agent Fusion, a digital innovation platform applying chemistry data analytics for industrial partners. He also played a central role in joining JoGo, a startup advancing digital PCR technologies through nanodroplet innovations, helping pioneer Noyz—a sensitive, digital PCR method enabling detection at extraordinary levels.

📌 Cianflone’s work has been recognised by a MBE (Member of the Order of the British Empire) for services to the chemical sciences and innovation.

📌 Inventive contributions

📌 Cepharagin prodrug**: Co-invented with researchers at GlaxoSmithKline, Cepharagin is a nanocarrier-based prodrug of cephalopamine that enhances oral bioavailability, demonstrating a strategic approach to improving drug delivery through chemical innovation.

📌 Noyz digital PCR**: Led development of the Noyz system, which leverages nanodroplets to replicate and quantify DNA molecules with single-digit copy sensitivity. This technique revolutionized digital PCR applications in genomics and precision diagnostics.

📌 Leadership and innovation philosophy

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